|
Direction
|
| |
| 1.Introduction |
Compound
Fluorouracil Injection is a chemotherapy drug with various
characteristics of carrier, targeting and increase immunity.
The targeting system is able to directly deliver the liposome-coated
drug to the lesion then kill cancer cells without side
effects.
It is recommended to have two treatment courses for general
use then to re-evaluate after the treatment has done for
monitoring the efficiency, such as tumor markers in blood
sample or CT scan. |
| |
| 2.How
to use |
| *
|
A
treatment course will use 1200ml |
| *
|
It contains
Port-A and Intravenous infusion, both need to be
diluted by 500ml N.S. (Normal Saline) |
| * |
Using Port-A
drip can lead to the higher dosage and better efficiency |
|
|
| |
| |
A.
|
Port-A
(dosage for 19 days) |
|
| |
|
(1)
|
Be
sure to shake the ampulla about 15 minutes before
using.
|
|
| |
The
initial dose of compound fluorouracil is 2 amp (10ml/amp),
then increased to 4 amp. |
| |
|
|
|
+
|
| |
|
|
|
|
| (2) |
The
first day, add 2 amp into 500ml N.S and mix well. |
| |
|
|
|
|
| |
|
|
 |
| |
(3) |
Keep
dropping about 40 - 60 drop/min, the rate of dropping
must be controlled to drop over 3hours.
|
| |
|
The dose can be increased to 8 amp at the 8th day;
4 amp twice a day in the mornig and evening. |
|
| |
|
The
list of Port-A injection cycle
|
|
|
This
dose
|
Total
dose
|
Record
|
|
This
dose
|
Total
dose
|
Record
|
|
Day
1
|
20ml
|
20ml
|
Year/Month/Day
|
Day
12
|
80ml
|
650ml
|
Year/Month/Day
|
|
Day
2
|
30ml
|
50ml
|
Year/Month/Day
|
Day
13
|
80ml
|
730ml
|
Year/Month/Day
|
|
Day
3
|
40ml
|
90ml
|
Year/Month/Day
|
Day
14
|
80ml
|
810ml
|
Year/Month/Day
|
|
Day
4
|
40ml
|
130ml
|
Year/Month/Day
|
Day
15
|
80ml
|
890ml
|
Year/Month/Day
|
|
Day
5
|
40ml
|
170ml
|
Year/Month/Day
|
Day
16
|
80ml
|
970ml
|
Year/Month/Day
|
|
Day
6
|
40ml
|
210ml
|
Year/Month/Day
|
Day
17
|
80ml
|
1050ml
|
Year/Month/Day
|
|
Day
7
|
40ml
|
250ml
|
Year/Month/Day
|
Day
18
|
80ml
|
1130ml
|
Year/Month/Day
|
|
Day
8
|
80ml
|
330ml
|
Year/Month/Day
|
Day
19
|
70ml
|
1200ml
|
Year/Month/Day
|
|
Day
9
|
80ml
|
410ml
|
Year/Month/Day
|
Attention：This
injection must be diluted with 500 ml normal
saline.
|
|
Day
10
|
80ml
|
490ml
|
Year/Month/Day
|
|
Day
11
|
80ml
|
570ml
|
Year/Month/Day
|
|
|
| |
| B. |
Intravenous
infusion (dosage for about one month) |
|
1. |
Be
sure to shake the ampulla about 15 minutes before
using, and mix well with normal saline. |
| |
2. |
The initial
dose of compound fluorouracil injection is 2 ampullae
(10ml/ampulla) with 500 ml N.S a day slow drip in
order to avoid from phlebitis or venous sclerosis. |
| |
3. |
The does
can be increased to 4 ampullae with 500 ml a day
till the cycle has done. |
|
| |
|
|
| If
you have any questions about the details, please see the
Q & A
or contact us. |
| |
| 3.Notice |
| 1. |
At the beginning, patient can be injected by Intravenous
infusion for several days then change to use Port-A
drip. |
| 2. |
The ascitse patient, please dilute the drug with
5%G/W and drip slowly. |
| 3. |
It
is not recommended to use this drug with radiation
therapy at the same time. |
| 4. |
Using
carefully under these situation |
| |
a. |
White blood cell count lower than 3000/mm3, blood
platelet count lower than 50,000/mm3 |
| |
b. |
Infection,
bleeding and fever over than 38℃ |
| 5. |
During
the therapy, no patient has been forced to stop
the administration for overdose. |
| 6. |
After one or two treatment courses of this injection,
patient should return to the hospital for re-evaluation
by routine examinations. |
|
| |
E-Maill：lipo@liposomal.org